Histometric study of socket healing after tooth extraction in rats treated with diclofenac

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Histometric study of socket healing after tooth extraction in rats treated with diclofenac.

The purpose of the present study was to investigate if diclofenac administration interferes with the time course of alveolar wound healing in rats. Forty-two Wistar rats were used, 21 rats received 10 mg/kg/day of diclofenac one day before and 4 days after extraction of the right maxillary incisors and 21 rats received saline. The animals were sacrificed 7, 14 and 21 days after tooth extraction...

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Cigarette smoke inhalation influences bone healing of post-extraction tooth socket: a histometric study in rats.

The aim of this study was to evaluate, histometrically, the bone healing of the molar extraction socket just after cigarette smoke inhalation (CSI). Forty male Wistar rats were randomly assigned to a test group (animals exposed to CSI, starting 3 days before teeth extraction and maintained until sacrifice; n=20) and a control group (animals never exposed to CSI; n=20). Second mandibular molars ...

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Grafting of tooth extraction socket with inorganic bovine bone or bioactive glass particles: comparative histometric study in rats.

PURPOSE To compare histometrically, in rats, the bone healing after grafting the incisor extraction sockets with inorganic bovine bone or bioactive glass particles. MATERIAL The volume fraction of grafted materials and alveolar healing components was estimated in histologic images at the end of the second and ninth weeks postoperatively by a differential point-counting method. RESULTS Both ...

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Socket Preservation Procedure after Tooth Extraction

Various materials are used in modern dental and maxillofacial surgery for bone tissue substitution and reconstruction. All osteoplastic materials can be divided into four groups by origin: autogenic, allogenic, xenogenic and synthetic. Synthetic resorbable materials were intended as an inexpensive substitute for natural bone. Synthetic graft materials include various types of ceramics: tricalci...

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Extraction socket healing in rats treated with bisphosphonate: animal model for bisphosphonate related osteonecrosis of jaws in multiple myeloma patients.

AIM The aim of this study is to replicate both clinical and histological presentation of bisphosphonate induced osteonecrosis of the jaws (BONJ) in an animal model of the disease state. Successful recapitulation of a BONJ-like indication in an animal model will be useful for studying pathogenesis, as well as prevention and treatment strategies for BONJ. MATERIALS AND METHODS Eighty (80) rats ...

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ژورنال

عنوان ژورنال: Brazilian Dental Journal

سال: 2002

ISSN: 0103-6440

DOI: 10.1590/s0103-64402002000200003